Advances in the Immunopathogenesis of Multiple Sclerosis by Domencio Gambi (Engl

Description: Advances in the Immunopathogenesis of Multiple Sclerosis by Domencio Gambi, Allesandra Lugaresi, Paolo A. Muraro To provide an overview of the basic mechanisms possibly involved in MS lesion initiation and development, an international meeting was organized in the context of the annual Congress of the Italian Neuroimmunology Association (AINI), held at the University of Chieti, in Chieti Italy on 29 October 1998. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description This volume highlights recent advances in the basic mechanisms of the immunopathogenesis of multiple sclerosis. Written by scientists actively involved in leading research, it mainly focuses on aspects of autoreactive T cell activation. Progress in the field of blood-brain barrier damage pathophysiology, antigen presentation in the central nervous system and magnetic resonance imaging are also reported. Providing a rapid access to up-to-date, leading research on basic pathogenetic mechanisms of multiple sclerosis, this book is directed not only to neuroimmunologists, but also to a general neurological readership. Table of Contents 1 — The affinity spectrum of myelin basic protein-reactive T cells.- 2 — The naïve and memory MBP-reactive CD4+ T cell repertoire: implications for the autoimmune concept in multiple sclerosis.- 3 — From specificity to degeneracy to molecular mimicry: antigen recognition of human autoreactive and pathogen-specific CD4+ T cells.- 4 — Immune activation in the interface between innate immunity and adaptive response: in vitro studies and therapeutical implications.- 5 — Neuronal control of the immunological microenvironment in the CNS: implications on neuronal cell death and survival.- 6 — Levels of platelet-activating factor in cerebrospinal fluid and plasma of patients with relapsing-remitting multiple sclerosis.- 7 — The contribution of magnetic resonance imaging to the understanding of multiple sclerosis pathogenesis.- 8 — The role of proinflammatory cytokines in multiple sclerosis.- 9 — Experimental autoimmune encephalomyelitis in the common marmoset Callithrixjacchus. Promotional Springer Book Archives Long Description P.A. MURARO, A. LUGARESI, D. GAMBI Many of the pathological aspects of multiple sclerosis (MS) lesions have been known for over a century. It is only recently, however, that different patterns of demyelination have been linked to distinct pathways of immune-mediated tissue destruction. In particular, the inter-individual heterogeneity of MS lesions has suggested that different mechanisms may act in different patients, accounting for the variability observed in clinical course, immunological findings in peripheral blood and cere Details ISBN884700067X Pages 90 Publisher Springer Verlag Year 1999 ISBN-10 884700067X ISBN-13 9788847000674 Format Paperback Imprint Springer Verlag Place of Publication Milan Country of Publication Italy Edited by Paolo A. Muraro DEWEY 616.834079 Short Title ADVANCES IN THE IMMUNOPATHOGEN Language English Media Book Publication Date 1999-06-01 Edition 1999th Illustrations 6 Illustrations, black and white; 90 p. 6 illus. DOI 10.1007/b77433;10.1007/978-88-470-2269-0 Author Paolo A. Muraro Edition Description 1999 ed. Audience Undergraduate We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96349847;

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