Description: Autophagy of the Nervous System : Cellular Self-Digestion in Neurons and Neurological Diseases, Hardcover by Yue, Zhenyu (EDT); Chu, Charleen T. (EDT), ISBN 9814350443, ISBN-13 9789814350440, Brand New, Free shipping in the US What is autophagy? Why would neurons or other brain cells digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as a culprit or accomplice to cell death in others? How does dysfunction of autophagy contribute to neurological diseases and can it be repaired or restored? This book addresses these questions and provide an expert view of the emerging concepts in autophagy research, focusing on autophagic processes and regulation in neurons. Current experimental evidence for both evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented. Advances in our understanding of the complex interplay of autophagy induction and downregulation will be discussed in relation to the critical balance needed to modulate neuroprotection versus neurodegeneration in the context of neurological diseases including Alzheimer's, Parkinson's, Huntington's, ischemic-hypoxic and lysosomal diseases.
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Book Title: Autophagy of the Nervous System : Cellular Self-Digestion in Neurons and Neurological Diseases
Number of Pages: 426 Pages
Language: English
Publisher: World Industries Scientific Publishing Co Pte LTD
Publication Year: 2012
Topic: Neuroscience, Life Sciences / Neuroscience, Life Sciences / Cell Biology
Item Height: 0.9 in
Illustrator: Yes
Genre: Science, Medical
Item Weight: 0 Oz
Author: Charleen T. Chu
Item Length: 9 in
Item Width: 6.1 in
Format: Hardcover
