Description: Bile Acids and Their Receptors, Hardcover by Fiorucci, Stefano (EDT); Distrutti, Eleonora (EDT), ISBN 3030220044, ISBN-13 9783030220044, Brand New, Free shipping in the US This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.
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Book Title: Bile Acids and Their Receptors
Number of Pages: X, 378 Pages
Publication Name: Bile Acids and Their Receptors
Language: English
Publisher: Springer International Publishing A&G
Publication Year: 2019
Subject: Gastroenterology, Internal Medicine, Pharmacology
Type: Textbook
Item Weight: 26.3 Oz
Item Length: 9.3 in
Subject Area: Medical
Author: Eleonora Distrutti
Series: Handbook of Experimental Pharmacology Ser.
Item Width: 6.1 in
Format: Hardcover
