Cytokines, Stress, and Depression by Robert Dantzer (English) Paperback Book

Description: Cytokines, Stress, and Depression by Robert Dantzer, Emmanuelle E. Wollmann, Raz Yirmiya Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their involvement in several neurological diseases involving an inflammatory component, including multiple sclerosis, brain trauma, stroke, and Alzheimers disease. This movement started in the late eighties, and the corresponding field of research, known as neuroimmunology, is presently booming. In psychiatry, however, the relationship between cytokines and mental disorders was much less evident and took longer to materialize. The first indication that cytokines might be involved in psychopathology came from cancerology and internal medicine. Table of Contents Depression and Immunity.- Immune Correlates of Depression.- Major Depression and Activation of The Inflammatory Response System.- Cytokine Production in Depressed Patients.- Indicators of Immune Activation in Depressed Patients.- Brain Effects on Cytokines.- Mood and Cognitive Disorders in Cancer Patients Receiving Cytokine Therapy.- Mechanisms of the Behavioural Effects of Cytokines.- Effects of Cytokines on Glucocorticoid Receptor Expression And Function.- Effects of Cytokines on Cerebral Neurotransmission.- Inflammation and Brain Function under Basal Conditions and During Long-Term Elevation of Brain Corticotropin-Releasing Hormone Levels.- Effects of Stress on Cytokine Production and Actions.- Dynamic Regulation of Proinflammatory Cytokines.- Cross-Sensitization Between Immune And Non-Immune Stressors.- Effects of Cytokines and Cytokine Antagonists in Animal Models of Depression.- Anhedonic and Anxiogenic Effects of Cytokine Exposure.- Stress, Learned Helplessness, and Brain Interleukin-1?.- Stress, Depression, and The Role of Cytokines.- Effects of Antidepressants Cytokine Production and Action.- Is There Evidence for an Effect of Antidepressant Drugs on Immune Function?.- Cytokines, "Depression Due to A General Medical Condition," and Antidepressant Drugs.- Cytokines, Stress, and Depression. Promotional Springer Book Archives Long Description Cytokines had been characterized in the early eighties as communication mole Details ISBN1475786107 Language English Edition 99199th ISBN-10 1475786107 ISBN-13 9781475786101 Series Advances in Experimental Medicine and Biology Year 2013 Publication Date 2013-03-23 Imprint Springer-Verlag New York Inc. Place of Publication New York, NY Country of Publication United States Edited by Raz Yirmiya DEWEY 616.8527079 Short Title CYTOKINES STRESS & DEPRESSION Media Book Series Number 461 Illustrations XII, 338 p. AU Release Date 2013-03-23 NZ Release Date 2013-03-23 US Release Date 2013-03-23 UK Release Date 2013-03-23 Author Raz Yirmiya Pages 338 Publisher Springer-Verlag New York Inc. Edition Description Softcover reprint of the original 1st ed. 1999 Format Paperback Alternative 9780306461354 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96336132;

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