Description: Evolving Concepts in Sepsis and Septic Shock Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Peter Q. Eichacker, Jerome Pugin Format: Paperback Publisher: Springer-Verlag New York Inc., United States Imprint: Springer-Verlag New York Inc. ISBN-13: 9781461356257, 978-1461356257 Synopsis Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis.
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Book Title: Evolving Concepts in Sepsis and Septic Shock
Number of Pages: 195 Pages
Language: English
Publication Name: Evolving Concepts in Sepsis and Septic Shock
Publisher: Springer-Verlag New York Inc.
Publication Year: 2012
Subject: Medicine
Item Height: 235 mm
Item Weight: 326 g
Type: Textbook
Author: Peter Q. Eichacker, Jerome Pugin
Series: Perspectives on Critical Care Infectious Diseases
Item Width: 155 mm
Format: Paperback