Gene Expression Profiling by Microarrays: Clinical Implications by Wolf-Karsten

Description: Gene Expression Profiling by Microarrays by Wolf-Karsten Hofmann Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology. Author Biography Wolf-Karsten Hofmann, MD, PhD is Professor of Medicine in the Department of Hematology, Oncology and Transfusion Medicine, Charite – University Hospital, Berlin. For four successive years he received the Young Investigator Award of the American Society of Hematology, and in addition to his research publications has written many book chapters in haematology and oncology. Table of Contents Preface Eckhard Thiel; 1. Introduction Wolf-Karsten Hofmann; 2. Technique of microarrays: microarray platforms Sven de Vos; 3. Quantitative quality control of microarray experiments: toward accurate gene expression measurements Xujing Wang and Martin J. Hessner; 4. Statistical analysis of gene expression data David A. Elashoff; 5. Genomic stratification in patients with heart failure Tara A. Bullard, Frédérick Aguilar, Jennifer L. Hall and Burns C. Blaxall; 6. Gene expression profiling for the diagnosis of acute leukemias Torsten Haferlach, Alexander Kohlmann, Susanne Schnittger, Claudia Schoch and Wolfgang Kern; 7. Gene expression profiling can distinguish tumour subclasses of breast carcinomas Ingrid A. Hedenfalk; 8. Gene expression profiling in lymphoid malignancies Christof Burek, Elena Hartmann, Zhengrong Mao, German Ott and Andreas Rosenwald; 9. MRNA profiling of pancreatic beta cells: investigating mechanisms of diabetes Leentje Van Lommel, Yves Moreau, Daniel Pipeleers, Jean-Christophe Jonas and Frans Schuit; 10. Prediction of response and resistance to treatment by gene expression profiling Philipp Kiewe and Wolf-Karsten Hofmann. Promotional Reviews clinical applications of this promising diagnostic and prognostic technology in cancer and other diseases. Promotional "Headline" Reviews clinical applications of this promising diagnostic and prognostic technology in cancer and other diseases. Description for Bookstore Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Description for Library Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Details ISBN0521853966 Publisher Cambridge University Press Language English ISBN-10 0521853966 ISBN-13 9780521853965 Media Book Format Hardcover DEWEY 572.865 Year 2006 Imprint Cambridge University Press Subtitle Clinical Implications Place of Publication Cambridge Country of Publication United Kingdom Edition 1st Short Title GENE EXPRESSION PROFILING BY M Pages 262 DOI 10.1604/9780521853965 UK Release Date 2006-06-22 AU Release Date 2006-06-22 NZ Release Date 2006-06-22 Edited by Wolf-Karsten Hofmann Author Wolf-Karsten Hofmann Publication Date 2006-06-22 Alternative 9780511545849 Illustrations 4 Tables, unspecified; 20 Line drawings, unspecified; 41 Line drawings, color Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:148146989;

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