Mimicking the Extracellular Matrix: The Intersection of Matrix Biology and Bioma

Description: Mimicking the Extracellular Matrix by Gregory A. Hudalla, William L. Murphy Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research.Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles.The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials. Back Cover The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research. Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles. The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials. Flap The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research. Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles. The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials. Table of Contents Matrix biology: Extracellular matrix - Building function through complexity;Matrix biology: Gradients and patterns within the extracellular matrix;Matrix biology: ECM turnover and temporal fluctuation;Matrix biology: Structure assembly of maminin-rich matrices;Biomaterials: Incorporating ECM-derived molecular features in biomaterials;Biomaterials: Modulating and tuning synthetic extracellular matrix mechanics;Biomaterials: Protein interactions with glycosaminoglycan-based biomaterials for tissue engineering;Biomaterials: Spatial patterning of biomolecule presentation using biomaterial culture methods;Biomaterials: Controlling properties over time to mimic the dynamic extracellular matrix;Biomaterials: Supramolecular artificial extracellular matrices; Description for Bookstore Materials which are able to mimic the properties of the extracellular matrix are of great interest for many therapeutic and biomedical applications. Edited by leading experts in the field, this book brings together the current knowledge of extracellular matrix biology with the state-of-the-art of extracellular matrix-mimicking biomaterials. The book is suitable for both biologists and bioengineers interested in the extracellular matrix, and provides material scientists with a benchmark for future efforts to develop synthetic biomaterials as extracellular matrix mimics. Details ISBN1849738335 Year 2015 ISBN-10 1849738335 ISBN-13 9781849738330 Format Hardcover Author William L. Murphy Short Title MIMICKING THE EXTRACELLULAR MA Language English Media Book DEWEY 610.28 Subtitle The Intersection of Matrix Biology and Biomaterials Publication Date 2015-11-18 UK Release Date 2015-11-18 Imprint Royal Society of Chemistry Place of Publication Cambridge Country of Publication United Kingdom AU Release Date 2015-11-18 NZ Release Date 2015-11-18 Publisher Royal Society of Chemistry Edited by William L Murphy Illustrations No Audience Professional & Vocational Alternative 9781788018159 Pages 421 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:149539564;

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